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What's New: Antibiotic

The Antibiotic guidelines provide advice on managing almost 200 unique infections; from self-limiting infections treated in primary care, to life-threatening infections requiring intensive care support. This review of the guidelines has been staggered, with topics released across 2025 and 2026. Topics are grouped into 3 categories based on their stage of review.

  1. Topics completely revised or newly developed in the March, September and December 2025 releases.
  2. Topics under revision for publication in 2026. To ensure alignment across the guidelines, some of these topics were amended in March 2025 (identified by an amended date on the topic’s page).
  3. Topics that have recently undergone a complete review and did not require further comprehensive review for the 2025 and 2026 releases. To ensure alignment across the guidelines, some of these topics were amended in March 2025 (identified by an amended date on the topic’s page).

For a summary of significant changes in each release, see What’s new for:
During this review, areas in which evidence was lacking, insufficient or conflicting, and for which further research is warranted were identified. To support the research community, these evidence gaps are available on our website and are updated with each release.

For a summary of practice-changing updates made to the Antibiotic guidelines outside these major releases, see Updates.
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